Müller, T; Göhl, M; Lusebrink, I; Dettner, K; Seifert, K: Cicindeloine from Stenus cicindeloides – Isolation, Structure Elucidation, and Total Synthesis, European Journal of Organic Chemistry, 12, 2323-2330 (2012) | |
Abstract: The new piperideine alkaloid cicindeloine (3) was isolated from the pygidial glands of the beetles Stenus cicindeloides and Stenus solutus. The structure and absolute configuration of 3 were elucidated by NMR spectroscopy and asymmetric synthesis, respectively. A very efficient gram-scale synthesis of 3 was developed using an intramolecular aza-Wittig reaction as the final step. The synthetic route is comprised of 12 steps and proceeds in 20 % total yield. Nine of the 12 steps were conducted without column chromatography. |
BayCEER Colloquium: |
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Th. 2024-04-25 now Perspectives and challenges in the restoration and conservation of two isolated habitats: gypsum and cliffs |
BayCEER Short Courses: |
Fr. 2024-04-26 Mobile Film Making Workshop (for students of BayCEER) |
Ecological-Botanical Garden: |
Fr. 2024-04-26 Aktion | Kräuterreich & regional: Backkunst im ÖBG (zus. mit HWK) |
Fr. 2024-04-26 Führung | Erdbeer-Minze und Zimmerknoblauch: Gewürzkräuter |
Su. 2024-04-28 Führung | Den Sängern auf der Spur: Vogelstimmen im ÖBG (zus. mit LBV) |