|Jin, X; Wu, S; She, M; Jia, Y; Hao, L; Yin, B; Wang, L; Obst, M; Shen, Y; Zhang, Y; Li, J: Novel Fluorescein-Based Fluorescent Probe for Detecting H2S and Its Real Applications in Blood Plasma and Biological Imaging, Analytical Chemistry, 88, 11253-11260 (2016), online: 2016-10-26, doi:10.1021/acs.analchem.6b04087 [Link]|
A broad-spectrum fluorescent probe, which can be applied to monitoring H2S in various biological systems, has been rationally designed and synthesized. This specific probe was applied to localize the endogenous H2S in living Raw264.7 macrophage cells, HepG2 cells, and H9C2 cells. At the same time, the probe has successfully visualized CBS- and CSE- induced endogenous H2S production and monitored CBS and CSE activity in H9C2 cells. This probe could serve as a powerful molecular imaging tool to further explore the physiological function and the molecular mechanisms of endogenous H2S in living animal systems.
|Fr. 2020-07-10 now|
12th BayCEER Workshop 2020: "Call for Abstracts" is open
Extreme redox oscillations in freshwater re-flooded acid sulfate soil wetlands: Effects on Fe, S, and trace metals geochemical behavior
Dissolved organic matter quality in differently managed forest ecosystems
Signaling of rhizosphere microbiome: key for plant health, development and nutrition
BayCEER Workshop 2020
Why Science Communication?
Stoichiometric controls of C and N cycling
Flying halfway across the globe to dig in the dirt – a research stay in Bloomington, USA
Picky carnivorous plants?