Jin, X; Wu, S; She, M; Jia, Y; Hao, L; Yin, B; Wang, L; Obst, M; Shen, Y; Zhang, Y; Li, J: Novel Fluorescein-Based Fluorescent Probe for Detecting H2S and Its Real Applications in Blood Plasma and Biological Imaging, Analytical Chemistry, 88, 11253-11260 (2016), online: 2016-10-26, doi:10.1021/acs.analchem.6b04087 [Link] | |
Abstract: A broad-spectrum fluorescent probe, which can be applied to monitoring H2S in various biological systems, has been rationally designed and synthesized. This specific probe was applied to localize the endogenous H2S in living Raw264.7 macrophage cells, HepG2 cells, and H9C2 cells. At the same time, the probe has successfully visualized CBS- and CSE- induced endogenous H2S production and monitored CBS and CSE activity in H9C2 cells. This probe could serve as a powerful molecular imaging tool to further explore the physiological function and the molecular mechanisms of endogenous H2S in living animal systems. |
BayCEER Colloquium: |
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Th. 2021-01-21 The impact of trees on soil organic carbon dynamics in the Subarctic - Priming effects and microbial N mining |
Th. 2021-01-28 BayCEER Member Assembly |
Th. 2021-02-04 Investigating communal pathogen defense and its role in social evolution |
Th. 2021-04-15 - folgt - |
Th. 2021-04-22 - folgt - |
13.01.2020 Why Science Communication? |
24.05.2019 Stoichiometric controls of C and N cycling |
07.05.2019 Flying halfway across the globe to dig in the dirt – a research stay in Bloomington, USA |
16.04.2019 Picky carnivorous plants? |