Müller, T; Göhl, M; Lusebrink, I; Dettner, K; Seifert, K: Cicindeloine from Stenus cicindeloides – Isolation, Structure Elucidation, and Total Synthesis, European Journal of Organic Chemistry, 12, 2323-2330 (2012)
Abstract:
The new piperideine alkaloid cicindeloine (3) was isolated from the pygidial glands of the beetles Stenus cicindeloides and Stenus solutus. The structure and absolute configuration of 3 were elucidated by NMR spectroscopy and asymmetric synthesis, respectively. A very efficient gram-scale synthesis of 3 was developed using an intramolecular aza-Wittig reaction as the final step. The synthetic route is comprised of 12 steps and proceeds in 20 % total yield. Nine of the 12 steps were conducted without column chromatography.

There are additional file downloads belonging to this publication

Password
Upcoming ...

BayCEER Colloquium:
Th. 2017-12-21
Silicon in biogeochemistry
Th. 2018-01-11
Biodiversity conservation under complex socio-ecological settings - the Colombian case
Th. 2018-01-18
Effects of climate change on plants and ecosystem functioning of managed temperate grasslands
Ökologisch-Botanischer Garten:
Su. 2018-01-07
Stärk´ anlaufen: Winterspaziergang im ÖBG
Su. 2018-01-07
Musikalischer Jahresbeginn mit den Rockin´ Dinos
Weather research site
Luftdruck (356m): 976.5 hPa
Lufttemperatur: 1.6 °C
Niederschlag: 0.7 mm/24h
Sonnenschein: <1 h/d
Wind (Höhe 17m): 10.6 km/h
Wind (Max.): 18.7 km/h
Windrichtung: W

...more