Stephan Clemens: Publikationen
Peer reviewed
2025
Hollmann, F., Weber, M., Aarts, M., Clemens, S.: Engineering of nicotianamine synthesis enhances cadmium mobility in plants and results in higher seed cadmium concentrations. The Plant Journal, 122(2), e70181 (2025).
doi:10.1111/tpj.70181
Thiébaut, N., Sarthou, M., Richtmann, L., Pergament Persson, D., Ranjan, A., Schloesser, M., Boutet, S., Rezende, L., Clemens, S., Verbruggen, N., Hanikenne, M.: Specific redox and iron homeostasis responses in the root tip of Arabidopsis upon zinc excess. New Phytologist, (2025).
doi:10.1111/nph.70105
2024
Clemens, S., Eroglu, S., Grillet, L., Nozoye, T.: Editorial: Metal transport in plants, volume II. Frontiers in Plant Science, 15 (2024).
doi:10.3389/fpls.2024.1395567
Richtmann, L., Opel, T., Maier, M., Langhof, N., Clemens, S.: Establishment of a system to analyze effects of airborne ultra-fine particulate matter from brake wear on plants under realistic exposure conditions. Journal of Hazardous Materials, 469, 134084 (2024).
doi:10.1016/j.jhazmat.2024.134084
Łuczkowski, M., Leszczyńska, W., Wątły, J., Clemens, S., Krężel, A.: Phytochelatins Bind Zn(II) with Micro- to Picomolar Affinities without the Formation of Binuclear Complexes, Exhibiting Zinc Buffering and Muffling Rather than Storing Functions. Inorganic Chemistry, 63(24), 10915-10931 (2024).
doi:10.1021/acs.inorgchem.4c01707
2023
Colina Blanco, A., Pischke, E., Higa Mori, A., Kerl, C., Clemens, S., Planer-Friedrich, B.: In Planta Arsenic Thiolation in Rice and Arabidopsis thaliana. Environmental Science & Technology, 57(51), 21846-21854 (2023).
doi:10.1021/acs.est.3c06603
Clemens, S.: Roots dOdge streSs. Molecular Plant, 16(12), 1885-1886 (2023).
doi:10.1016/j.molp.2023.10.013
Liu, X., Ju, Y., Mandzhieva, S., Pinskii, D., Minkina, T., Rajput, V., Roane, T., Huang, S., Li, Y., Ma, L., Clemens, S., Rensing, C.: Sporadic Pb accumulation by plants : Influence of soil biogeochemistry, microbial community and physiological mechanisms. Journal of Hazardous Materials, 444, 130391 (2023).
doi:10.1016/j.jhazmat.2022.130391
Strenkert, D., Schmollinger, S., Hu, Y., Hofmann, C., Holbrook, K., Liu, H., Purvine, S., Nicora, C., Chen, S., Lipton, M., Northen, T., Clemens, S., Merchant, S.: Zn deficiency disrupts Cu and S homeostasis in Chlamydomonas resulting in over accumulation of Cu and Cysteine. Metallomics, 15(7), mfad043 (2023).
doi:10.1093/mtomcs/mfad043
2022
Clemens, S.: The cell biology of Zn. Journal of Experimental Botany, 73(6), 1688-1698 (2022).
doi:10.1093/jxb/erab481
Planer-Friedrich, B., Kerl, C., Colina Blanco, A., Clemens, S.: Dimethylated Thioarsenates : A Potentially Dangerous Blind Spot in Current Worldwide Regulatory Limits for Arsenic in Rice. Journal of Agricultural and Food Chemistry, 70(31), 9610-9618 (2022).
doi:10.1021/acs.jafc.2c02425
Pischke, E., Barozzi, F., Colina Blanco, A., Kerl, C., Planer-Friedrich, B., Clemens, S.: Dimethylmonothioarsenate Is Highly Toxic for Plants and Readily Translocated to Shoots. Environmental Science & Technology, 56(14), 10072-10083 (2022).
doi:10.1021/acs.est.2c01206
Clemens, S.: CRISPR/Cas als neue Chance der Gentechnik für Lebensmittel. Zeitschrift für das gesamte Lebensmittelrecht, 49(4), 428-443 (2022).
Assunção, A., Cakmak, I., Clemens, S., González-Guerrero, M., Nawrocki, A., Thomine, S.: Micronutrient homeostasis in plants for more sustainable agriculture and healthier human nutrition. Journal of Experimental Botany, 73(6), 1789-1799 (2022).
doi:10.1093/jxb/erac014
2021
Clemens, S.: Casting a wide cross-species transcriptomics net : convergent evolution of nickel hyperaccumulation. New Phytologist, 229(2), 653-655 (2021).
doi:10.15495/EPub_UBT_00005290
Purnhagen, K., Clemens, S., Eriksson, D., Fresco, L., Tosun, J., Qaim, M., Visser, R., Weber, A., Wesseler, J., Zilberman, D.: Europe's Farm to Fork Strategy and Its Commitment to Biotechnology and Organic Farming : Conflicting or Complementary Goals?. Trends in Plant Science, 26(6), 600-606 (2021).
doi:10.1016/j.tplants.2021.03.012
Clemens, S.: (Not) an elementary question : How to mobilize the iron in the wall?. Molecular Plant, 14(10), 1610-1611 (2021).
doi:10.1016/j.molp.2021.08.009
Gebauer, G., Clemens, S.: Stealing sugar from the honey fungus. Plant, Cell & Environment, 44(1), 17-19 (2021).
doi:10.1111/pce.13909
2020
Höreth, S., Pongrac, P., van Elteren, J., Debeljak, M., Vogel-Mikuš, K., Weber, M., Braun, M., Pietzenuk, B., Pečovnik, M., Vavpetič, P., Pelicon, P., Arčon, I., Krämer, U., Clemens, S.: Arabidopsis halleri shows hyperbioindicator behaviour for Pb and leaf Pb accumulation spatially separated from Zn. New Phytologist, 226(2), 492-506 (2020).
doi:10.1111/nph.16373
Weber, M., Beyene, B., Nagler, N., Herfert, J., Schempp, S., Klecker, M., Clemens, S.: A mutation in the essential and widely conserved DAMAGED DNA BINDING1-Cullin4 ASSOCIATED FACTOR gene OZS3 causes hypersensitivity to zinc excess, cold and UV stress in Arabidopsis thaliana. The Plant Journal, 103(3), 995-1009 (2020).
doi:10.15495/EPub_UBT_00005027
Spielmann, J., Ahmadi, H., Scheepers, M., Weber, M., Nitsche, S., Carnol, M., Bosman, B., Kroymann, J., Motte, P., Clemens, S., Hanikenne, M.: The two copies of the zinc and cadmium ZIP6 transporter of Arabidopsis halleri have distinct effects on cadmium tolerance. Plant, Cell & Environment, 43(9), 2143-2157 (2020).
doi:10.15495/EPub_UBT_00005297
2019
Uraguchi, S., Weber, M., Clemens, S.: Elevated root nicotianamine concentrations are critical for Zn hyperaccumulation across diverse edaphic environments. Plant, Cell & Environment, 42(6), 2003-2014 (2019).
doi:10.1111/pce.13541
Kumar, V., Vogelsang, L., Seidel, T., Schmidt, R., Weber, M., Reichelt, M., Meyer, A., Clemens, S., Sharma, S., Dietz, K.: Interference between arsenic-induced toxicity and hypoxia. Plant, Cell & Environment, 42(2), 574-590 (2019).
doi:10.1111/pce.13441
Vetter, V., Walter, J., Wilfahrt, P., Buhk, C., Braun, M., Clemens, S., Dinkel, E., Dubbert, M., Schramm, A., Wegener, F., Werner, C., Jentsch, A.: Invasion windows for a global legume invader are revealed after joint examination of abiotic and biotic filters. Plant Biology, 21(5), 832-843 (2019).
doi:10.1111/plb.12987
Clemens, S.: Metal ligands in micronutrient acquisition and homeostasis. Plant, Cell & Environment, 42(10), 2902-2912 (2019).
doi:10.1111/pce.13627
Kerl, C., Schindele, R., Brüggenwirth, L., Colina Blanco, A., Rafferty, C., Clemens, S., Planer-Friedrich, B.: Methylated Thioarsenates and Monothioarsenate Differ in Uptake, Transformation, and Contribution to Total Arsenic Translocation in Rice Plants. Environmental Science & Technology, 53(10), 5787-5796 (2019).
doi:10.1021/acs.est.9b00592
Clemens, S.: Safer food through plant science : reducing toxic element accumulation in crops. Journal of Experimental Botany, 70(20), 5537-5557 (2019).
doi:10.1093/jxb/erz366
Detterbeck, A., Nagel, M., Rensch, S., Weber, M., Börner, A., Persson, D., Schjørring, J., Christov, V., Clemens, S.: The search for candidate genes associated with natural variation of grain Zn accumulation in barley. Biochemical Journal, 476(13), 1889-1909 (2019).
doi:10.1042/BCJ20190181
2018
Ahmadi, H., Corso, M., Weber, M., Verbruggen, N., Clemens, S.: CAX1 suppresses Cd-induced generation of reactive oxygen species in Arabidopsis halleri. Plant, Cell & Environment, 41(10), 2435-2448 (2018).
doi:10.1111/pce.13362
Uraguchi, S., Sone, Y., Ohta, Y., Ohkama-Ohtsu, N., Hofmann, C., Hess, N., Nakamura, R., Takanezawa, Y., Clemens, S., Kiyono, M.: Identification of C-terminal Regions in Arabidopsis thaliana Phytochelatin Synthase 1 Specifically Involved in Activation by Arsenite. Plant & Cell Physiology, 59(3), 500-509 (2018).
doi:10.1093/pcp/pcx204
Kerl, C., Rafferty, C., Clemens, S., Planer-Friedrich, B.: Monothioarsenate Uptake, Transformation, and Translocation in Rice Plants. Environmental Science & Technology, 52(16), 9154-9161 (2018).
doi:10.1021/acs.est.8b02202
2017
Gruntman, M., Anders, C., Mohiley, A., Laaser, T., Clemens, S., Höreth, S., Tielbörger, K.: Clonal integration and heavy-metal stress : responses of plants with contrasting evolutionary backgrounds. Evolutionary Ecology, 31(3), 305-316 (2017).
doi:10.1007/s10682-016-9840-9
Benáková, M., Ahmadi, H., Dučaiová, Z., Tylová, E., Clemens, S., Tůma, J.: Effects of Cd and Zn on physiological and anatomical properties of hydroponically grown Brassica napus plants.. Environmental Science and Pollution Research, 24(25), 20705-20716 (2017).
doi:10.1007/s11356-017-9697-7
Clemens, S.: How metal hyperaccumulating plants can advance Zn biofortification. Plant and Soil, 411(1-2), 111-120 (2017).
doi:10.1007/s11104-016-2920-3
Fischer, S., Spielau, T., Clemens, S.: Natural variation in Arabidopsis thaliana Cd responses and the detection of quantitative trait loci affecting Cd tolerance. Scientific Reports, 7, 3693 (2017).
doi:10.1038/s41598-017-03540-z
Uraguchi, S., Tanaka, N., Hofmann, C., Abiko, K., Ohkama-Ohtsu, N., Weber, M., Kamiya, T., Sone, Y., Nakamura, R., Takanezawa, Y., Kiyono, M., Fujiwara, T., Clemens, S.: Phytochelatin Synthase has Contrasting Effects on Cadmium and Arsenic Accumulation in Rice Grains. Plant & Cell Physiology, 58(10), 1730-1742 (2017).
doi:10.1093/pcp/pcx114
Stein, R., Höreth, S., de Melo, J., Syllwasschy, L., Lee, G., Garbin, M., Clemens, S., Krämer, U.: Relationships between soil and leaf mineral composition are element-specific, environment-dependent and geographically structured in the emerging model Arabidopsis halleri. New Phytologist, 213(3), 1274-1286 (2017).
doi:10.1111/nph.14219
Planer-Friedrich, B., Kühnlenz, T., Halder, D., Lohmayer, R., Wilson, N., Rafferty, C., Clemens, S.: Thioarsenate toxicity and tolerance in the model system Arabidopsis thaliana. Environmental Science & Technology, 51(12), 7187-7196 (2017).
doi:10.1021/acs.est.6b06028
2016
Suryawanshi, V., Talke, I., Weber, M., Eils, R., Brors, B., Clemens, S., Krämer, U.: Between-species differences in gene copy number are enriched among functions critical for adaptive evolution in Arabidopsis halleri. BMC Genomics, 17(Suppl. 13), 1034 (2016).
doi:10.1186/s12864-016-3319-5
Clemens, S., Weber, M.: The essential role of coumarin secretion for Fe acquisition from alkaline soil. Plant Signaling & Behavior, 11(2), e1114197 (2016).
doi:10.1080/15592324.2015.1114197
Kühnlenz, T., Hofmann, C., Uraguchi, S., Schmidt, H., Schempp, S., Weber, M., Lahner, B., Salt, D., Clemens, S.: Phytochelatin Synthesis Promotes Leaf Zn Accumulation of Arabidopsis thaliana Plants Grown in Soil with Adequate Zn Supply and is Essential for Survival on Zn-Contaminated Soil. Plant & Cell Physiology, 57(11), 2342-2352 (2016).
doi:10.1093/pcp/pcw148
Farooq, M., Detterbeck, A., Clemens, S., Dietz, K.: Silicon-induced reversibility of cadmium toxicity in rice. Journal of Experimental Botany, 67(11), 3573-3585 (2016).
doi:10.1093/jxb/erw175
Detterbeck, A., Pongrac, P., Rensch, S., Reuscher, S., Pečovnik, M., Vavpetič, P., Pelicon, P., Holzheu, S., Krämer, U., Clemens, S.: Spatially resolved analysis of variation in barley (Hordeum vulgare) grain micronutrient accumulation. New Phytologist, 211(4), 1241-1254 (2016).
doi:10.1111/nph.13987
Clemens, S., Ma, J.: Toxic heavy metal and metalloid accumulation in crop plants and foods. Annual Review of Plant Biology, 67, 489-512 (2016).
doi:10.1146/annurev-arplant-043015-112301
2015
Cornu, J., Deinlein, U., Höreth, S., Braun, M., Schmidt, H., Weber, M., Persson, D., Husted, S., Schjørring, J., Clemens, S.: Contrasting effects of nicotianamine synthase knockdown on zinc and nickel tolerance and accumulation in the zinc/cadmium hyperaccumulator Arabidopsis halleri. New Phytologist, 206(2), 738-750 (2015).
doi:10.1111/nph.13237
Kühnlenz, T., Westphal, L., Schmidt, H., Scheel, D., Clemens, S.: Expression of Caenorhabditis elegans PCS in the AtPCS1-deficient Arabidopsis thaliana cad1-3 mutant separates the metal tolerance and non-host resistance functions of phytochelatin synthases. Plant, Cell & Environment, 38(11), 2239-2247 (2015).
doi:10.1111/pce.12534
2014
Fischer, S., Kühnlenz, T., Thieme, M., Schmidt, H., Clemens, S.: Analysis of plant Pb tolerance at realistic submicromolar concentrations demonstrates the role of phytochelatin synthesis for Pb detoxification. Environmental Science & Technology, 48(13), 7552-7559 (2014).
doi:10.1021/es405234p
Kühnlenz, T., Schmidt, H., Uraguchi, S., Clemens, S.: Arabidopsis thaliana phytochelatin synthase 2 is constitutively active in vivo and can rescue the growth defect of the PCS1-deficient cad1-3 mutant on Cd-contaminated soil. Journal of Experimental Botany, 65(15), 4241-4253 (2014).
doi:10.1093/jxb/eru195
Uraguchi, S., Kamiya, T., Clemens, S., Fujiwara, T.: Characterization of OsLCT1, a cadmium transporter from indica rice (Oryza sativa). Physiologia Plantarum, 151(3), 339-347 (2014).
doi:10.1111/ppl.12189
Halimaa, P., Lin, Y., Ahonen, V., Blande, D., Clemens, S., Gyenesei, A., Häikiö, E., Kärenlampi, S., Laiho, A., Aarts, M., Pursiheimo, J., Schat, H., Schmidt, H., Tuomainen, M., Tervahauta, A.: Gene expression differences between Noccaea caerulescens ecotypes help to identify candidate genes for metal phytoremediation. Environmental Science & Technology, 48(6), 3344-3353 (2014).
doi:10.1021/es4042995
Schmidt, H., Günther, C., Weber, M., Spörlein, C., Loscher, S., Böttcher, C., Schobert, R., Clemens, S.: Metabolome analysis of Arabidopsis thaliana roots identifies a key metabolic pathway for iron acquisition. PLoS One, 9(7), e102444 (2014).
doi:10.1371/journal.pone.0102444
Clemens, S.: Zn and Fe biofortification: the right chemical environment for human bioavailability. Plant Science, 225, 52-57 (2014).
doi:10.1016/j.plantsci.2014.05.014
2013
Hanikenne, M., Kroymann, J., Trampczynska, A., Bernal, M., Motte, P., Clemens, S., Krämer, U.: Hard selective sweep and ectopic gene conversion in a gene cluster affording environmental adaptation. PLoS Genetics, 9(8), e1003707 (2013).
doi:10.1371/journal.pgen.1003707
Verbruggen, N., Hanikenne, M., Clemens, S.: A more complete picture of metal hyperaccumulation through next-generation sequencing technologies. Frontiers in Plant Science, 4, 388 (2013).
doi:10.3389/fpls.2013.00388
Weber, M., Deinlein, U., Fischer, S., Rogowski, M., Geimer, S., Tenhaken, R., Clemens, S.: A mutation in the Arabidopsis thaliana cell wall biosynthesis gene pectin methylesterase 3 as well as its aberrant expression cause hypersensitivity specifically to Zn. The Plant Journal, 76(1), 151-164 (2013).
doi:10.1111/tpj.12279
Palmer, C., Hindt, M., Schmidt, H., Clemens, S., Guerinot, M.: MYB10 and MYB72 are required for growth under iron-limiting conditions. PLoS Genetics, 9(11), e1003953 (2013).
doi:10.1371/journal.pgen.1003953
Clemens, S., Deinlein, U., Ahmadi, H., Höreth, S., Uraguchi, S.: Nicotianamine is a major player in plant Zn homeostasis. Biometals, 26(4), 623-632 (2013).
doi:10.1007/s10534-013-9643-1
Clemens, S., Aarts, M., Thomine, S., Verbruggen, N.: Plant Science : the key to preventing slow cadmium poisoning. Trends in Plant Science, 18(2), 92-99 (2013).
doi:10.1016/j.tplants.2012.08.003
2012
Deinlein, U., Weber, M., Schmidt, H., Rensch, S., Trampczynska, A., Hansen, T., Husted, S., Schjørring, J., Talke, I., Krämer, U., Clemens, S.: Elevated nicotianamine levels in Arabidopsis halleri roots play a key role in zinc hyperaccumulation. The Plant Cell, 24(2), 708-723 (2012).
doi:10.1105/tpc.111.095000
2011
Gasber, A., Klaumann, S., Trentman, O., Trampczynska, A., Clemens, S., Schneider, S., Sauer, N., Feifer, I., Bittner, F., Mendel, R., Neuhaus, E.: Identification of an Arabidopsis solute carrier critical for intracellular transport and interorgan allocation of molybdate. Plant Biology, 13(5), 710-718 (2011).
doi:10.1111/j.1438-8677.2011.00448.x
Meyer, C., Peisker, D., Courbot, M., Cracium, A., Cazalé, A., Desgain, D., Schat, H., Clemens, S., Verbruggen, N.: Isolation and characterization of Arabidopsis halleri and Thlaspi caerulescens phytochelatin synthases. Planta, 234(1), 83-95 (2011).
doi:10.1007/s00425-011-1378-z
2010
Wojas, S., Clemens, S., Skłodowska, A., Antosiewicz, D.: Arsenic response of AtPCS1- and CePCS-expressing plants : Effects of external As(V) concentration on As-accumulation pattern and NPT metabolism. Journal of Plant Physiology, 167(3), 169-175 (2010).
doi:10.1016/j.jplph.2009.07.017
Isaure, M., Sarret, G., Harada, E., Choi, Y., Marcus, M., Fakra, S., Geoffroy, N., Pairis, S., Susini, J., Clemens, S., Manceau, A.: Calcium promotes cadmium elimination as vaterite grains by tobacco trichomes. Geochimica et Cosmochimica Acta, 74(20), 5817-5834 (2010).
doi:10.1016/j.gca.2010.07.011
Harada, E., Kim, J., Meyer, A., Hell, R., Clemens, S., Choi, Y.: Expression Profiling of Tobacco Leaf Trichomes Identifies Genes for Biotic and Abiotic Stresses. Plant & Cell Physiology, 51(10), 1627-1637 (2010).
doi:10.1093/pcp/pcq118
Trampczynska, A., Küpper, H., Meyer-Klaucke, W., Schmidt, H., Clemens, S.: Nicotianamine forms complexes with Zn(II) in vivo. Metallomics, 2(1), 57-66 (2010).
doi:10.1039/b913299f
Wojas, S., Ruszczynska, A., Bulska, E., Clemens, S., Antosiewicz, D.: The role of subcellular distribution of cadmium and phytochelatins in the generation of distinct phenotypes of AtPCS1- and CePCS3-expressing tobacco. Journal of Plant Physiology, 167(12), 981-988 (2010).
doi:10.1016/j.jplph.2010.02.010
2009
Böttcher, C., von Roepenack-Lahaye, E., Schmidt, J., Clemens, S., Scheel, D.: Analysis of Phenolic Choline Esters from Seeds of Arabidopsis thaliana and Brassica napus by Capillary Liquid Chromatography/Electrospray-Tandem Mass Spectrometry. Journal of Mass Spectrometry, 44(4), 466-476 (2009).
doi:10.1002/jms.1522
Lin, Y., Liang, H., Yang, S., Boch, A., Clemens, S., Chen, C., Wu, J., Huang, J., Yeh, K.: Arabidopsis IRT3 is a zinc-regulated and plasma membrane localized zinc/iron transporter. New Phytologist, 182(2), 392-404 (2009).
doi:10.1111/j.1469-8137.2009.02766.x
Clemens, S., Peršoh, D.: Multi-tasking phytochelatin synthases. Plant Science, 177(4), 266-271 (2009).
doi:10.1016/j.plantsci.2009.06.008
Tennstedt, P., Peisker, D., Böttcher, C., Trampczynska, A., Clemens, S.: Phytochelatin synthesis is essential for the detoxification of excess Zn and contributes significantly to the accumulation of Zinc. Plant Physiology, 149(2), 938-948 (2009).
doi:10.1104/pp.108.127472
Clemens, S., Naumann, B., Hippler, M.: Proteomics of metal mediated protein dynamics in plants : iron and cadmium in the focus. Frontiers in Bioscience, 14, 1955-1969 (2009).
doi:10.2741/3355
Khandal, D., Samol, I., Buhr, F., Pollmann, S., Schmidt, H., Clemens, S., Reinbothe, C., Reinbothe, S.: Singlet oxygen-dependent translational control in the tigrina-d.12 mutant of barley". Proceedings of the National Academy of Sciences of the United States of America, 106(31), 13112-13117 (2009).
doi:10.1073/pnas.0903522106
2008
Boch, A., Trampczynska, A., Simm, C., Taudte, N., Krämer, U., Clemens, S.: Loss of Zhf and the tightly regulated zinc-uptake system SpZrt1 in Schizosaccharomyces pombe reveals the delicacy of cellular zinc balance. FEMS Yeast Research, 8(6), 883-896 (2008).
doi:10.1111/j.1567-1364.2008.00414.x
Böttcher, C., von Roepenack-Lahaye, E., Schmidt, J., Schmotz, C., Neumann, S., Scheel, D., Clemens, S.: Metabolome Analysis of Biosynthetic Mutants Reveals a Diversity of Metabolic Changes and Allows Identification of a Large Number of New Compounds in Arabidopsis. Plant Physiology, 147(4), 2107-2120 (2008).
doi:10.1104/pp.108.117754
Wojas, S., Clemens, S., Hennig, J., Skłodowska, A., Kopera, E., Schat, H., Bal, W., Antosiewicz, D.: Overexpression of phytochelatin synthase in tobacco : distinctive effects of AtPCS1 and CePCS1 genes on plant response to cadmium. Journal of Experimental Botany, 59(8), 2205-2219 (2008).
doi:10.1093/jxb/ern092
Palmgren, M., Clemens, S., Williams, L., Krämer, U., Borg, S., Schjørring, J., Sanders, D.: Zinc biofortification of cereals : problems and solutions. Trends in Plant Science, 13(9), 464-473 (2008).
doi:10.1016/j.tplants.2008.06.005
2007
Böttcher, C., von Roepenack-Lahaye, E., Willscher, E., Scheel, D., Clemens, S.: Evaluation of matrix effects in metabolite profiling based on capillary liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry. Analytical Chemistry, 79(4), 1507-1513 (2007).
doi:10.1021/ac061037q
2006
Weber, M., Trampczynska, A., Clemens, S.: Comparative transcriptome analysis of toxic metal responses in Arabidopsis thaliana and the Cd2+-hypertolerant facultative metallophyte Arabidopsis halleri. Plant, Cell & Environment, 29(5), 950-963 (2006).
doi:10.1111/j.1365-3040.2005.01479.x
Clemens, S.: Evolution and function of phytochelatin synthases. Journal of Plant Physiology, 163(3), 319-332 (2006).
doi:10.1016/j.jplph.2005.11.010
Roth, U., von Roepenack-Lahaye, E., Clemens, S.: Proteome changes in Arabidopsis thaliana roots upon exposure to Cd2+. Journal of Experimental Botany, 57(15), 4003-4013 (2006).
doi:10.1093/jxb/erl170
Clemens, S.: Toxic metal accumulation, responses to exposure and mechanisms of tolerance in plants. Biochimie, 88(11), 1707-1719 (2006).
doi:10.1016/j.biochi.2006.07.003
Trampczynska, A., Böttcher, C., Clemens, S.: The transition metal chelator nicotianamine is synthesized by filamentous fungi. FEBS Letters, 580(13), 3173-3178 (2006).
doi:10.1016/j.febslet.2006.04.073
Sarret, G., Harada, E., Choi, Y., Isaure, M., Geoffroy, N., Fakra, S., Marcus, M., Clemens, S., Manceau, A., Birschwilks, M.: Trichomes of tobacco excrete zinc as zinc-substituted calcium carbonate and other zinc-containing compounds. Plant Physiology, 141(3), 1021-1034 (2006).
doi:10.1104/pp.106.082743
Grzam, A., Tennstedt, P., Clemens, S., Hell, R., Meyer, A.: Vacuolar sequestration of glutathione S-conjugates outcompetes a possible degradation of the glutathione moiety by phytochelatin synthase. FEBS Letters, 580(27), 6384-6390 (2006).
doi:10.1016/j.febslet.2006.10.050
2004
Weber, M., Harada, E., Vess, C., von Roepenack-Lahaye, E., Clemens, S.: Comparative microarray analysis of Arabidopsis thaliana and Arabidopsis halleri roots identifies nicotianamine synthase, a ZIP transporter and other genes as potential metal hyperaccumulation factors. The Plant Journal, 37(2), 269-281 (2004).
doi:10.1046/j.1365-313X.2003.01960.x
Harada, E., von Roepenack-Lahaye, E., Clemens, S.: A cyanobacterial protein with similarity to phytochelatin synthases catalyzes the conversion of glutathione to γ-glutamylcysteine and lacks phytochelatin synthase activity. Phytochemistry, 65(24), 3179-3185 (2004).
doi:10.1016/j.phytochem.2004.09.017
von Roepenack-Lahaye, E., Degenkolb, T., Zerjeski, M., Franz, M., Roth, U., Wessjohann, L., Schmidt, J., Scheel, D., Clemens, S.: Profiling of Arabidopsis secondary metabolites by capillary liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry. Plant Physiology, 134(2), 548-559 (2004).
doi:10.1104/pp.103.032714
2003
Marković-Housley, Z., Degano, M., Lamba, D., von Roepenack-Lahaye, E., Clemens, S., Susani, M., Ferreira, F., Scheiner, O., Breiteneder, H.: Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier. Journal of Molecular Biology, 325(1), 123-133 (2003).
doi:10.1016/S0022-2836(02)01197-X
Maier, T., Yu, C., Küllertz, G., Clemens, S.: Localization and functional characterization of metal-binding sites in phytochelatin synthases. Planta, 218(2), 300-308 (2003).
doi:10.1007/s00425-003-1091-7
Wysocki, R., Clemens, S., Augustyniak, D., Golik, P., Maciaszczyk, E., Tamás, M., Dziadkowiec, D.: Metalloid tolerance based on phytochelatins is not functionally equivalent to the arsenite transporter Acr3p. Biochemical and Biophysical Research Communications, 304(2), 293-300 (2003).
doi:10.1016/S0006-291X(03)00584-9
Clemens, S., Simm, C.: Schizosaccharomyces pombe as a model for metal homeostasis in plant cells : the phytochelatin-dependent pathway is the main Cd detoxification mechanism. New Phytologist, 159(2), 323-330 (2003).
doi:10.1046/j.1469-8137.2003.00811.x
2002
Bloss, T., Clemens, S., Nies, D.: Characterization of the ZAT1p zinc transporter from Arabidopsis thaliana in microbial model organisms and reconstituted proteoliposomes. Planta, 214(5), 783-791 (2002).
doi:10.1007/s00425-001-0677-1
Clemens, S., Palmgren, M., Krämer, U.: A long way ahead : understanding and engineering plant metal accumulation. Trends in Plant Science, 7(7), 309-315 (2002).
doi:10.1016/S1360-1385(02)02295-1
Clemens, S., Bloss, T., Vess, C., Neumann, D., Nies, D., zur Nieden, U.: A transporter in the endoplasmic reticulum of Schizosaccharomyces pombe cells mediates zinc storage and differentially affects transition metal tolerance. The Journal of Biological Chemistry, 277(20), 18215-18221 (2002).
doi:10.1074/jbc.M201031200
2001
Cazalé, A., Clemens, S.: Arabidopsis thaliana expresses a second functional phytochelatin synthase. FEBS Letters, 507(2), 215-219 (2001).
doi:10.1016/S0014-5793(01)02976-3
Clemens, S., Schroeder, J., Degenkolb, T.: Caenorhabditis elegans expresses a functional phytochelatin synthase. European Journal of Biochemistry, 268(13), 3640-3643 (2001).
doi:10.1046/j.1432-1327.2001.02293.x
Clemens, S.: Developing tools for phytoremediation : towards a molecular understanding of plant metal tolerance and accumulation. International Journal of Occupational Medicine and Environmental Health, 14(3), 235-239 (2001).
Clemens, S.: Molecular mechanisms of plant metal tolerance and homeostasis. Planta, 212(4), 475-486 (2001).
doi:10.1007/s004250000458
1999
Baizabal-Aguirre, V., Clemens, S., Uozumi, N., Schroeder, J.: Suppression of inward-rectifying K+ Channels KAT1 and AKT2 by dominant negative point mutations in the KAT1 alpha-subunit. Journal of Membrane Biology, 167(2), 119-125 (1999).
doi:10.1007/s002329900476
Clemens, S., Kim, E., Neumann, D., Schroeder, J.: Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast. The EMBO Journal, 18(12), 3325-3333 (1999).
doi:10.1093/emboj/18.12.3325
1998
Clemens, S., Antosiewicz, D., Ward, J., Schachtman, D., Schroeder, J.: The plant cDNA LCT1 mediates the uptake of calcium and cadmium in yeast. Proceedings of the National Academy of Sciences of the United States of America, 95(20), 12043-12048 (1998).
doi:10.1073/pnas.95.20.12043
Books and Book sections
2024
Clemens, S., Fehse, B., Walter, J., Bartfeld, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Müller-Terpitz, R., Mundlos, S., Reich, J., Winkler, E., Zenke, M.: Handlungsempfehlungen zur Genomeditierung bei Pflanzen. In: Stephan Clemens, Boris Fehse (eds.): Im Fokus: Genomeditierung von Pflanzen : Eine aktuelle Bestandsaufnahme der Arbeitsgruppe Gentechnologiebericht. - Berlin : Berlin Institute of Health at Charité (BIH), 2024. - 10-16.
doi:10.17169/refubium-45156
Clemens, S., Fehse, B.: Im Fokus: Genomeditierung von Pflanzen : Eine aktuelle Bestandsaufnahme der Arbeitsgruppe Gentechnologiebericht. - Berlin : Berlin Institute of Health at Charité (BIH), 2024. - 176
doi:10.17169/refubium-45156
Clemens, S.: Die Potenziale der Genomeditierung für eine nachhaltigere Landwirtschaft nutzen. In: Stephan Clemens, Boris Fehse (eds.): Im Fokus: Genomeditierung von Pflanzen : Eine aktuelle Bestandsaufnahme der Arbeitsgruppe Gentechnologiebericht. - Berlin : Berlin Institute of Health at Charité (BIH), 2024. - 88-89.
doi:10.17169/refubium-45156
2023
Clemens, S.: Genom-Editierung für mehr Lebensmittelsicherheit. In: Neue genomische Techniken : Rechtliche Bewertungen, Anwendungen und Herausforderungen. - Erlangen : 2023. - 15-25.
Fehse, B., Walter, J., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Müller-Terpitz, R., Mundlos, S., Reich, J., Schicktanz, S., Winkler, E., Zenke, M.: Handlungsempfehlungen zur somatischen Gentherapie, Keimbahninterventionen und Zelltherapie. In: Boris Fehse, Hannah Schickl, Sina Bartfeld, Martin Zenke (eds.): Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft : AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. - Berlin : Springer, 2023. - 1-10.
doi:10.1007/978-3-662-67908-1_1
2021
Fünfter Gentechnologiebericht : Sachstand und Perspektiven für Forschung und Anwendung. - Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E., Zenke, M. (eds.). - Baden-Baden : Nomos, 2021.
doi:10.5771/9783748927242
Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Fehse, B., Hampel, J., Hucho, F., Korte, M., Mundlos, S., Reich, J., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E., Zenke, M.: Handlungsempfehlungen zu den Themenfeldern der IAG Gentechnologiebericht. In: Fünfter Gentechnologiebericht : Sachstand und Perspektiven für Forschung und Anwendung. - Baden-Baden : Nomos, 2021. - 47-80.
doi:10.5771/9783748927242-47
Clemens, S.: Themenbereich Grüne Gentechnologie: mit Genomeditierung zum Neustart?. In: Fünfter Gentechnologiebericht : Sachstand und Perspektiven für Forschung und Anwendung. - Baden-Baden : Nomos, 2021. - 184-205.
doi:10.5771/9783748927242-184
2020
Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Fehse, B., Hampel, J., Hucho, F., Korte, M., Mundlos, S., Reich, J., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E., Zenke, M.: Kernaussagen und Handlungsempfehlungen zu Organoiden. In: Sina Bartfeld, Hannah Schickl, Cantas Alev, Bon-Kyoung Koo, Anja Pichl, Angela Osterheider, Lilian Marx-Stölting (eds.): Organoide : Ihre Bedeutung für Forschung, Medizin und Gesellschaft. - Baden-Baden : Nomos, 2020. - 13-28.
doi:10.5771/9783748908326-13
2019
Clemens, S.: Genome Editing und das Gentechnikrecht: Naturwissenschaftliche Einführung. In: Markus Möstl (eds.): Das Lebensmittelrecht zwischen Verbraucherschutz und Agrarpolitik : Kennzeichnung, Überwachung, Vermarktung. - Frankfurt am Main : Fachmedien Recht und Wirtschaft, dfv Mediengruppe, 2019. - 71-82.
2013
Clemens, S.: Lead in plants. In: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov (eds.): Encyclopedia of Metalloproteins. - New York : Springer, 2013. - 1179-1183.
doi:10.1007/978-1-4614-1533-6_323
Clemens, S.: Mercury in plants. In: Kretsinger, Robert H. ; Uversky, Vladimir N. ; Permyakov, Eugene A. (Hrsg.): Encyclopedia of Metalloproteins. - New York : Springer, 2013. - 1352-1356.
doi:10.1007/978-1-4614-1533-6_313
2010
Clemens, S.: Zn - A Versatile Player in Plant Cell Biology. In: Hell, Rüdiger (Hrsg.): Cell Biology of Metals and Nutrients. - Berlin : Springer, 2010. - 281-298.
2006
Clemens, S., Böttcher, C., Franz, M., Willscher, E., Roepenack-Lahaye, E., Scheel, D.: Capillary HPLC coupled to electrospray ionization quadrupole time-of-flight mass spectrometry. In: Saito, Kazuki ; Dixon, Richard A. ; Willmitzer, Lothar (Hrsg.): Plant metabolomics. - Berlin : Springer, 2006. - 65-79.
doi:10.1007/3-540-29782-0_5
2005
Krämer, U., Clemens, S.: Functions and Homeostasis of Zinc, Copper, and Nickel in plants. In: Tamás, Markus J. (Hrsg.): Molecular biology of metal homeostasis and detoxification : from microbes to man. - Berlin : Springer, 2005. - 215-271.
2003
Clemens, S., Simm, C., Maier, T.: Heavy metal-binding proteins and peptides. In: Alexander Steinbüchel, Stephen R. Fahnestock (eds.): Biopolymers. Vol. 8. Polyamides and complex proteinaceous materials II. - Weinheim : Wiley-VCH, 2003. - 255-288.
doi:10.1002/3527600035.bpol8010
2002
Clemens, S., Thomine, S., Schroeder, J.: Molecular mechanisms that control plant tolerance to heavy metals and possible roles towards manipulating metal accumulation. In: Kirsi-Marja Oksman-Caldentey, Wolfgang Barz (eds.): Plant Biotechnology and Transgenic Plants. - New York : Dekker, 2002. - 665-691.
Other publications
2018
Kaiser, M., Clemens, S.: Neue Fakultät VII am Campus Kulmbach. UBT aktuell, (2), 13 (2018).
2011
Schmidt, H., Böttcher, C., Trampczynska, A., Clemens, S.: Use of recombinantly produced 15N3-labelled nicotianamine for fast and sensitive stable isotope dilution ultra-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry, 399(3), 1355-1361 (2011).
doi:10.1007/s00216-010-4436-7